Celecoxib-d4 [544686-20-6]

MedChem Express

Celecoxib-d4 [544686-20-6]

10

544686-20-6

Research Use Only

C17H10D4F3N3O2S

385.40

Celecoxib-d4 is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an?analog?of Celecoxib and with the optimal yield of 75%[1].

FC(F)(C1=NN(C2=C([2H])C([2H])=C(C([2H])=C2[2H])S(N)(=O)=O)C(C3=CC=C(C=C3)C)=C1)F

-20°C,2°C to 8°C

12352200