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Non-hydrolyzable ATP Test Kit, screening kit for ATP-binding proteins (NK-101) by Jena Bioscience. Preferred supplier for academia & industry

NK-101 Non-hydrolyzable ATP Test Kit, screening kit for AT...

Non-hydrolyzable ATP Test Kit, screening kit for ATP-binding proteins

The enzymes involved in hydrolysis of nucleoside triphosphates are a major focus of biochemical research, targeting the understanding and treatment of cellular processes involved in diseases such as cancer, viral infections, cardiovascular and motional disorders. To elucidate the mechanisms of action of these enzymes, it is often desirable to trap the enzymes in their triphosphate-bound state. Since natural nucleotides are hydrolyzed at rates usually preventing such studies, nucleotide analogs are used that are hydrolyzed at much smaller rates or that are even completely resistant to hydrolysis. The Non-hydrolyzable ATP Test Kit contains a set of 5 typical non-hydrolyzable Adenosine-5-triphosphate analogs. The position of the modification within the triphosphate exerts influence on its binding affinity to a particular enzyme and its hydrolysis rate. This Kit is designed to identify the most suitable non-hydrolyzable ATP derivative for your application.

Non-hydrolyzable GTP Test Kit, screening kit for GTP-binding proteins (NK-102) by Jena Bioscience. Preferred supplier for academia & industry

NK-102 Non-hydrolyzable GTP Test Kit, screening kit for GT...

Non-hydrolyzable GTP Test Kit, screening kit for GTP-binding proteins

The enzymes involved in hydrolysis of nucleoside triphosphates are a major focus of biochemical research, targeting the understanding and treatment of cellular processes involved in diseases such as cancer, viral infections, cardiovascular and motional disorders. To elucidate the mechanisms of action of these enzymes, it is often desirable to trap the enzymes in their triphosphate-bound state. Since natural nucleotides are hydrolyzed at rates usually preventing such studies, nucleotide analogs are used that are hydrolyzed at much smaller rates or that are even completely resistant to hydrolysis. The Non-hydrolyzable GTP Test Kit contains a set of 5 typical non-hydrolyzable Guanosine-5-triphosphate analogs. The position of the modification within the triphosphate exerts influence on its binding affinity to a particular enzyme and its hydrolysis rate. This Kit is designed to identify the most suitable non-hydrolyzable GTP derivative for your application.

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