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Biolaminin 521 LN

Biolaminin 521 LN

Research Use Only
LN521
BioLamina
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    BioLamina
  • Product Name
    Biolaminin 521 LN
  • Delivery Days Customer
    9
  • Category Supplier
    Protein
  • Certification
    Research Use Only
  • Concentration
    0.1 mg/ml
  • Scientific Description
    Biolaminin 521 LN is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free and animal origin-free stem cell culture system. LN521 is animal origin-free to the primary level.
  • Storage Instruction
    -20°C to -80°C
  • UNSPSC
    12352202

References

  • Rodin S, Antonsson L, Hovatta O, Tryggvason K. Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc. 2014;9(10):2354-68.
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  • Laperle A, Hsiao C, Lampe M, et al. α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Stem Cell Reports. 2015;5(2):195-206.
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  • Zhang D, Yang S, Toledo EM, et al. Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Sci Signal. 2017;10(493)
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  • Lu HF, Chai C, Lim TC, et al. A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells. Biomaterials. 2014;35(9):2816-26.
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  • Miyazaki T, Nakatsuji N, Suemori H. Optimization of slow cooling cryopreservation for human pluripotent stem cells. Genesis. 2014;52(1):49-55.
    Read more
  • Bergström R, Ström S, Holm F, Feki A, Hovatta O. Xeno-free culture of human pluripotent stem cells. Methods Mol Biol. 2011;767:125-36.
    Read more

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