Overview
- SupplierBioLamina
- Product NameBiolaminin 521 MX
- Delivery Days Customer7
- CertificationResearch Use Only
- Concentration0.1 mg/ml
- Scientific DescriptionBiolaminin 521 MX is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free, and animal origin-free stem cell culture system. MX521 enables efficient single-cell passaging of genetically stable and pluripotent stem cells without the need for any apoptosis inhibitors for the superior quality of your cells and studies.
- Storage InstructionRepeated freeze/thaw should be avoided
- UNSPSC12352202
References
- Rodin S, Antonsson L, Niaudet C, et al. Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Nat Commun. 2014;5:3195.Read more
- Rodin S, Antonsson L, Hovatta O, Tryggvason K. Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc. 2014;9(10):2354-2368.Read more
- Laperle A, Hsiao C, Lampe M, et al. Α-5 laminin synthesized by human pluripotent stem cells promotes self-renewal. Stem Cell Reports. 2015;5(2):195-206.Read more
- Albalushi H, Kurek M, Karlsson L, et al. Laminin 521 stabilizes the pluripotency expression pattern of human embryonic stem cells initially derived on feeder cells. Stem Cells Int. 2018;2018:7127042.Read more
- Zhang D, Yang S, Toledo EM, et al. Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Sci Signal. 2017;10(493):eaal4165.Read more
