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Biolaminin 521 MX

Biolaminin 521 MX

Research Use Only
MX521
BioLamina
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    BioLamina
  • Product Name
    Biolaminin 521 MX
  • Delivery Days Customer
    9
  • Category Supplier
    Protein
  • Certification
    Research Use Only
  • Concentration
    0.1 mg/ml
  • Scientific Description
    Biolaminin 521 MX is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free stem cell culture system. MX521 is animal origin-free to the secondary level.
  • Storage Instruction
    -20°C to -80°C
  • UNSPSC
    12352202

References

  • Rodin S, Antonsson L, Niaudet C, et al. Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Nat Commun. 2014;5:3195.
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  • Rodin S, Antonsson L, Hovatta O, Tryggvason K. Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc. 2014;9(10):2354-2368.
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  • Laperle A, Hsiao C, Lampe M, et al. Α-5 laminin synthesized by human pluripotent stem cells promotes self-renewal. Stem Cell Reports. 2015;5(2):195-206.
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  • Albalushi H, Kurek M, Karlsson L, et al. Laminin 521 stabilizes the pluripotency expression pattern of human embryonic stem cells initially derived on feeder cells. Stem Cells Int. 2018;2018:7127042.
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  • Zhang D, Yang S, Toledo EM, et al. Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Sci Signal. 2017;10(493):eaal4165.
    Read more

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