
WB analysis of Jurkat cells using GTX45813 CENPB antibody at 0.2-1microg/ml.
CENPB antibody, C-term
GTX45813
Overview
- SupplierGeneTex
- Product NameCENPB antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID1059
- Target nameCENPB
- Target descriptioncentromere protein B
- Target synonymsCENP-B; centromere autoantigen B; centromere protein B, 80kDa; major centromere autoantigen B
- HostRabbit
- IsotypeIgG
- Protein IDP07199
- Protein NameMajor centromere autoantigen B
- Scientific DescriptionThis gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203