CEP-1347

MedChem Express

CEP-1347 [156177-65-0]

10

156177-65-0

Research Use Only

98.50

C33H33N3O5S2

615.76

CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects. CEP-1347 blocks JNK1 activation induced by members of the mixed lineage kinase (MLK) family (MLK3, MLK2, MLK1, dual leucine zipper kinase, and leucine zipper kinase). As an inhibitor of MDM4 , CEP-1347 can more effectively inhibit the growth of glioma cells expressing wild-type p53 [1] [2] [3] [4] [5] [6] .

C[C@]12N3C4=C(C5=CC(CSCC)=CC=C53)C(CNC6=O)=C6C(C7=C8)=C4N([C@@H](C[C@]2(O)C(OC)=O)O1)C7=CC=C8CSCC

-20°C

12352200