CEP-28122 mesylate salt

TargetMol Chemicals

CEP-28122 mesylate salt

14

Chemical

Research Use Only

CEP-28122 mesylate salt

C29H39ClN6O6S

635.17

CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) inhibitor with an IC50 value of 1.9 nM against recombinant ALK kinase activity. It shows antitumor efficacy in ALK-positive human cancer models and has favorable pharmacodynamic and pharmacokinetic profiles.

3 years

COC1=C(C=CC2=C1CC[C@H](CC2)N3CCOCC3)NC4=NC=C(C(=N4)N[C@@H]5[C@@H]6C[C@H]([C@@H]5C(=O)N)C=C6)Cl.CS(=O)(=O)O

-20°C

12352200