CEP-8983 [374071-46-2]
HY-14688
CAS Number374071-46-2
Product group Chemicals
Molecular Weight306.32
Overview
- SupplierMedChem Express
- Product NameCEP-8983 [374071-46-2]
- Delivery Days Customer14
- CAS Number374071-46-2
- CertificationResearch Use Only
- Molecular FormulaC18H14N2O3
- Molecular Weight306.32
- Scientific DescriptionCEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560)[1].
- SMILESCOC1=CC=CC2=C1C3=C(C(NC4=O)=O)C4=C(CCC5)C5=C3N2
- UNSPSC12131703