Bio-Connect

CEP-8983 [374071-46-2]

HY-14688
MedChem Express
CAS Number374071-46-2
Product group Chemicals
Molecular Weight306.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CEP-8983 [374071-46-2]
  • Delivery Days Customer
    14
  • CAS Number
    374071-46-2
  • Certification
    Research Use Only
  • Molecular Formula
    C18H14N2O3
  • Molecular Weight
    306.32
  • Scientific Description
    CEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560)[1].
  • SMILES
    COC1=CC=CC2=C1C3=C(C(NC4=O)=O)C4=C(CCC5)C5=C3N2
  • UNSPSC
    12131703