Cephaeline [483-17-0]
HY-N4118
Overview
- SupplierMedChem Express
- Product NameCephaeline [483-17-0]
- Delivery Days Customer10
- CAS Number483-17-0
- CertificationResearch Use Only
- Estimated Purity98.94
- Molecular FormulaC28H38N2O4
- Molecular Weight466.61
- Scientific DescriptionCephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy[1][2][3][4].
- SMILESOC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC
- Storage Instruction2°C to 8°C
- UNSPSC12352200