Cephaeline

MedChem Express

Cephaeline [483-17-0]

10

483-17-0

98.94

C28H38N2O4

466.61

Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus ( ZIKV ) and Ebola virus ( EBOV ) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells ( MEC ), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy [1] [2] [3] [4] .

OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC

2°C to 8°C

12352200