Cephalochromin

MedChem Express

Cephalochromin [25908-26-3]

5

25908-26-3

Research Use Only

C28H22O10

518.47

Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI). Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC50 of 1.9 and 1.8 microM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 microg/mL[1].

OC(C(C(C=C1O[C@@H](C2)C)=[C@@](C(O)=C3)[C@@](C(O)=C4)=C(C=C5O[C@@H](C6)C)C(C(O)=C5C6=O)=C4O)=C3O)=C1C2=O

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