Ceranib-2 [1402830-75-4]

MedChem Express

Ceranib-2 [1402830-75-4]

10

1402830-75-4

Research Use Only

99.25

C25H19NO3

381.42

Ceranib-2 is a potent and nonlipid ceramidase inhibitor that inhibits cellular ceramidase activity with an IC50 of 28 microM in SKOV3 cells. Ceranib-2 induces the accumulation of multiple ceramide species, decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and induces cell apoptosis. Anticancer activity[1][2].

O=C1NC(C=CC=C2)=C2C(C3=CC=CC=C3)=C1C(/C=C/C4=CC=C(C=C4)OC)=O

-20°C,2°C to 8°C

12352200