CERK Polyclonal Antibody

Reddot Biotech

CERK Polyclonal Antibody

5

0.4 mg/ml

CERK

ceramide kinase

acylsphingosine kinase; ceramide kinase; dA59H18.2; dA59H18.3; hCERK; lipid kinase 4; lipid kinase LK4; LK4

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

-20°C

12352203