Bio-Connect

CERK Polyclonal Antibody

Research Use Only
RD77845A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCERK
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CERK Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.4 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64781
  • Target name
    CERK
  • Target description
    ceramide kinase
  • Target synonyms
    acylsphingosine kinase; ceramide kinase; dA59H18.2; dA59H18.3; hCERK; lipid kinase 4; lipid kinase LK4; LK4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203