Cetrelimab [2050478-92-5]
HY-P99499
Product group Antibodies
Overview
- SupplierMedChem Express
- Product NameCetrelimab [2050478-92-5]
- Delivery Days Customer10
- CAS Number2050478-92-5
- CertificationResearch Use Only
- Estimated Purity99.0
- Scientific DescriptionCetrelimab (JNJ 63723283; JNJ 3283) is a human IgG4kappa mAb targeting PD-1. Cetrelimab binds PD-1 (Kd=1.72 nM, HEK293) to block the interaction of PD-1 with PD-L1 and PD-L2 (IC50s=111.7 ng/mL and 138.6 ng/mL, respectively). Cetrelimab stimulates peripheral T cells, increases IFN-gamma, IL-2, TNF-alpha level and inhibits tumor growth in vivo[1].
- Storage Instruction-80°C
- UNSPSC41116161