![CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF594 conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2018/10/BNUB2290-1.jpeg "CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF594 conjugate, 0.1mg/mL [26628-22-8]")
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF594 conjugate, 0.1mg/mL [26628-22-8]
BNC942290
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rabbit
TargetCFTR
Overview
- SupplierBiotium
- Product NameCFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF594 conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCFTR/2290R
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID1080
- Target nameCFTR
- Target descriptionCF transmembrane conductance regulator
- Target synonymsABC35; ABCC7; cAMP-dependent chloride channel; CF; CFTR/MRP; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulating; cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); dJ760C5.1; MRP7; TNR-CFTR
- HostRabbit
- IsotypeIgG
- Protein IDP13569
- Protein NameCystic fibrosis transmembrane conductance regulator
- Scientific DescriptionThis antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3,5-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse, Rabbit
- Storage Instruction2°C to 8°C
- UNSPSC12352203