cGAS-IN-1 [858770-07-7]

MedChem Express

cGAS-IN-1 [858770-07-7]

5

858770-07-7

Research Use Only

98.29

C18H19NO8

377.35

cGAS-IN-1 (Compound C20) is a cyclic GMP-AMP synthase (cGAS) inhibitor with IC50s of 2.28 microM (human cGAS, h-cGASFL) and 1.44 microM (mouse cGAS, m-cGASCD). cGAS-IN-1 can be used for the studies of autoimmune diseases and chronic inflammation[1].

COC1=CC2=C(C(C)=C(CCC(N(CC(O)=O)CC(O)=O)=O)C(O2)=O)C=C1

-20°C,2°C to 8°C

12131703