CGH2466 (dihydrochloride)
HY-103167
CAS Number1177618-54-0
Product group Chemicals
Molecular Weight395.13
Overview
- SupplierMedChem Express
- Product NameCGH2466 (dihydrochloride)
- Delivery Days Customer5
- CAS Number1177618-54-0
- CertificationResearch Use Only
- Molecular FormulaC14H11Cl4N3S
- Molecular Weight395.13
- Scientific DescriptionCGH 2466 dihydrochloride is an orally active adenosine A1, A2B and A3 receptor antagonist with the IC50 values of 19 nM, 21 nM, and 80 nM respectively. CGH 2466 dihydrochloride inhibits p38 MAPK (IC50 = 187~ 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 dihydrochloride displays potent anti-inflammatory effects both in vitro and in vivo, and can be used for research on asthma and chronic obstructive pulmonary disease (COPD)[1].
- SMILESNC1=NC(C2=CC=C(Cl)C(Cl)=C2)=C(C3=CC=NC=C3)S1.Cl.Cl
- UNSPSC12352200
