CGP-74514 (hydrochloride) [481724-82-7]
HY-118976
CAS Number481724-82-7
Product group Chemicals
Molecular Weight422.35
Overview
- SupplierMedChem Express
- Product NameCGP-74514 (hydrochloride) [481724-82-7]
- Delivery Days Customer999
- CAS Number481724-82-7
- CertificationResearch Use Only
- Molecular FormulaC19H25Cl2N7
- Molecular Weight422.35
- Scientific DescriptionCGP-74514 hydrochloride is a highly selective cyclin-dependent kinase 1 (CDK1) inhibitor (IC50: 25 nM). CGP-74514 hydrochloride inhibits CDK1/cyclin B complex activity, arrests the cell cycle at G2/M phase and induces tumor cell apoptosis. CGP-74514 hydrochloride is promising for research of bladder cancer[1][2].
- SMILESCCN1C2=NC(N[C@@H]3[C@@H](CCCC3)N)=NC(NC4=CC(Cl)=CC=C4)=C2N=C1.Cl
- UNSPSC12352200