CGP-78608 [206648-13-7]

MedChem Express

CGP-78608 [206648-13-7]

5

206648-13-7

Research Use Only

C11H13BrN3O5P

378.12

CGP 78608 is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). CGP 78608 has anticonvulsant activities[1][2].

C[C@H](P(O)(O)=O)NCC1=CC(Br)=CC(NC2=O)=C1NC2=O

12352200