CGP 78608 (hydrochloride)

MedChem Express

CGP 78608 (hydrochloride) [1135278-54-4]

10

1135278-54-4

Research Use Only

99.56

C11H14BrClN3O5P

414.58

CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor , with an IC 50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC 50 in the low nM range (26.3 nM). Anticonvulsant activity [1] [2] .

OP(O)([C@H](NCC1=CC(Br)=CC(NC2=O)=C1NC2=O)C)=O.[H]Cl

-20°C

12352200