CGP-82996

MedChem Express

CGP-82996 [359886-84-3]

5

359886-84-3

Research Use Only

98.12

C27H32N6O

456.58

GP-82996 (CINK4) is a pharmacological inhibitor of CDK4/6. GP-82996 has IC50s of 1.5, 5.6 and 25 microM for CDK4/cyclin D1, CDK6/cyclin D1 and Cdk5/p35, respectively. GP-82996 induces the apoptosis of cancer cells U2OS. GP-82996 can be used in the research of cancer[1][2].

O[C@H]1CC[C@H](NC2=NC(NC3=CC4=C(N(CC5=CC=CC=C5)C=C4)C=C3)=NC(NCC)=C2)CC1

-20°C,2°C to 8°C

12352200