CGP77675 (hydrate)
HY-W062835A
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameCGP77675 (hydrate)
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC26H29N5O2.xH2O
- Scientific DescriptionCGP77675 hydrate is an orally active and potent inhibitor of Src family kinases. CGP77675 hydrate inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src ( IC 50 s of 5-20 and 40 nM, respectively),and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC 50 s of 0.02, 0.15, 1.0, 0.31, and 0.29 microM, respectively. Anticancer activity [1] .
- SMILESOC1CCN(CCC2=CC=C(N3C=C(C4=CC=CC(OC)=C4)C5=C(N)N=CN=C53)C=C2)CC1.O.[x]
- UNSPSC12352200