Bio-Connect

CGP77675 (hydrate)

HY-W062835A
MedChem Express
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CGP77675 (hydrate)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C26H29N5O2.xH2O
  • Scientific Description
    CGP77675 hydrate is an orally active and potent inhibitor of Src family kinases. CGP77675 hydrate inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src ( IC 50 s of 5-20 and 40 nM, respectively),and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC 50 s of 0.02, 0.15, 1.0, 0.31, and 0.29 microM, respectively. Anticancer activity [1] .
  • SMILES
    OC1CCN(CCC2=CC=C(N3C=C(C4=CC=CC(OC)=C4)C5=C(N)N=CN=C53)C=C2)CC1.O.[x]
  • UNSPSC
    12352200