CGS35066 [261619-50-5]

MedChem Express

CGS35066 [261619-50-5]

14

261619-50-5

Research Use Only

C16H16NO6P

349.28

CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 microM, respectively[1].

O=P(O)(O)CN[C@H](C(O)=O)CC1=CC=C(C2=CC=CC=C2O3)C3=C1

RT

12352200