CH6953755

MedChem Express

CH6953755 [2055918-71-1]

10

2055918-71-1

Research Use Only

99.45

C26H22F2N6O4S

552.55

CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC 50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo [1] .

CS(=O)(NC1=CC2=C(C=C1C)C=C(C(C3=C(N)N(C4=C(C)C=C(OC5=C(F)C=CC=C5F)N=C4)N=C3)=O)N2)=O

-20°C,2°C to 8°C

12352200