CH6953755 [2055918-71-1]

MedChem Express

CH6953755 [2055918-71-1]

10

2055918-71-1

Research Use Only

99.45

C26H22F2N6O4S

552.55

CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo[1].

CS(=O)(NC1=CC2=C(C=C1C)C=C(C(C3=C(N)N(C4=C(C)C=C(OC5=C(F)C=CC=C5F)N=C4)N=C3)=O)N2)=O

-20°C,2°C to 8°C

12352200