The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA634200(CHAC1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA634200(CHAC1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
CHAC1 Antibody
CSB-PA634200
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCHAC1
Overview
- SupplierCusabio
- Product NameCHAC1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79094
- Target nameCHAC1
- Target descriptionChaC glutathione specific gamma-glutamylcyclotransferase 1
- Target synonymsblocks Notch protein; botch; ChaC, cation transport regulator homolog 1; ChaC, cation transport regulator-like 1; gamma-GCG 1; gamma-GCT acting on glutathione homolog 1; glutathione-specific gamma-glutamylcyclotransferase 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9BUX1
- Protein NameGlutathione-specific gamma-glutamylcyclotransferase 1
- Scientific DescriptionCHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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