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CHAC1 antibody [N1C3]

Name: CHAC1 antibody [N1C3]
SKU: GTX120775_G10
Availability: BackOrder

GTX120775

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman, Mouse

TargetCHAC1

Overview

Supplier
GeneTex
Product Name
CHAC1 antibody [N1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID79094
Target name
CHAC1
Target description
ChaC glutathione specific gamma-glutamylcyclotransferase 1
Target synonyms
blocks Notch protein; botch; ChaC, cation transport regulator homolog 1; ChaC, cation transport regulator-like 1; gamma-GCG 1; gamma-GCT acting on glutathione homolog 1; glutathione-specific gamma-glutamylcyclotransferase 1
Host
Rabbit
Isotype
IgG
Protein IDQ9BUX1
Protein Name
Glutathione-specific gamma-glutamylcyclotransferase 1
Scientific Description
Pro-apoptotic component of the unfolded protein response pathway. May mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis. Tseng HH et al., 2021 Sep 24, Mol Ther Oncolytics
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The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer. Samanta S et al., 2021 Apr 1, Cancer Res
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Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Crinelli R et al., 2021 Jan 26, Antioxidants (Basel)
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The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Chen PH et al., 2017 Apr, Neuropharmacology
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