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CHAC1 antibody [N1C3]

GTX120775
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
TargetCHAC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CHAC1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID79094
  • Target name
    CHAC1
  • Target description
    ChaC glutathione specific gamma-glutamylcyclotransferase 1
  • Target synonyms
    blocks Notch protein; botch; ChaC, cation transport regulator homolog 1; ChaC, cation transport regulator-like 1; gamma-GCG 1; gamma-GCT acting on glutathione homolog 1; glutathione-specific gamma-glutamylcyclotransferase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BUX1
  • Protein Name
    Glutathione-specific gamma-glutamylcyclotransferase 1
  • Scientific Description
    Pro-apoptotic component of the unfolded protein response pathway. May mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis. Tseng HH et al., 2021 Sep 24, Mol Ther Oncolytics
    Read more
  • The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer. Samanta S et al., 2021 Apr 1, Cancer Res
    Read more
  • Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Crinelli R et al., 2021 Jan 26, Antioxidants (Basel)
    Read more
  • The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Chen PH et al., 2017 Apr, Neuropharmacology
    Read more

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