Chapsyn-110 Antibody (OASE00173)

Aviva Systems Biology

Chapsyn-110 Antibody (OASE00173)

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

S18-30

1 mg/ml

Unconjugated

Dlg2

discs large MAGUK scaffold protein 2

Dlgh2, disks large homolog 2, channel-associated protein of synapse-110, chapsyn-110, discs, large homolog 2, disks large 1 tumor suppressor protein-like, postsynaptic density protein PSD-93, synaptic density protein PSD-93

Mouse

IgG1

Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA receptors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2).

-20°C

12352203