CHD3 antibody [2G4]

GeneTex

CHD3 antibody [2G4]

7

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

2G4

1 mg/ml

Unconjugated

CHD3

chromodomain helicase DNA binding protein 3

ATP-dependent helicase CHD3; CHD-3; chromodomain-helicase-DNA-binding protein 3; hZFH; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-ALPHA; SNIBCPS; ZFH; zinc finger helicase; zinc-finger helicase (Snf2-like)

Mouse

IgG1

Chromodomain-helicase-DNA-binding protein 3

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203