CHD3 Polyclonal Antibody

Reddot Biotech

CHD3 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

CHD3

chromodomain helicase DNA binding protein 3

ATP-dependent helicase CHD3; CHD-3; chromodomain-helicase-DNA-binding protein 3; hZFH; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-ALPHA; SNIBCPS; ZFH; zinc finger helicase; zinc-finger helicase (Snf2-like)

Rabbit

IgG

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

-20°C

12352203