CHD5 antibody

GeneTex

CHD5 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.88 mg/ml

Unconjugated

CHD5

chromodomain helicase DNA binding protein 5

ATP-dependent helicase CHD5; CHD-5; chromodomain-helicase-DNA-binding protein 5

Rabbit

IgG

Chromodomain-helicase-DNA-binding protein 5

Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 [PubMed 12592387]).[supplied by OMIM]

-20°C or -80°C,2°C to 8°C

12352203