Dactolisib (BEZ235) [915019-65-7]
S1009
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameDactolisib (BEZ235) [915019-65-7]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionDactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110alfa/gamma/delta/bèta and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.
- UNSPSC12352200