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BI-D1870

S2843
Selleck Chemicals
CAS Number501437-28-1
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    BI-D1870 [501437-28-1]
  • Delivery Days Customer
    9
  • CAS Number
    501437-28-1
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3beta, MARK3, CK1 and Aurora B. BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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