Laduviglusib (CHIR-99021)
S1263
CAS Number252917-06-9
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameLaduviglusib (CHIR-99021) [252917-06-9]
- Delivery Days Customer9
- CAS Number252917-06-9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionLaduviglusib (CHIR-99021, CT99021) is a GSK-3alpha and GSK-3beta inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3beta compared to CDKs. CHIR99021 functions as a Wnt/beta-catenin activator and induces autophagy.
- Storage Instruction-80°C
- UNSPSC51202000
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