Bio-Connect

Laduviglusib (CHIR-99021) [252917-06-9]

Research Use Only
S1263
Selleck Chemicals
CAS Number252917-06-9
Product group Chemicals
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Laduviglusib (CHIR-99021) [252917-06-9]
  • Delivery Days Customer
    9
  • CAS Number
    252917-06-9
  • Certification
    Research Use Only
  • Scientific Description
    CHIR-99021 (CT99021) is a GSK-3alfa and GSK-3bèta inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3bèta compared to CDKs. CHIR99021 functions as a Wnt/bèta-catenin activator and induces autophagy.
  • UNSPSC
    12352200