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GSK690693 [937174-76-0]

Research Use Only
S1113
Selleck Chemicals
CAS Number937174-76-0
Product group Chemicals
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Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    GSK690693 [937174-76-0]
  • Delivery Days Customer
    9
  • CAS Number
    937174-76-0
  • Certification
    Research Use Only
  • Scientific Description
    GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1.
  • UNSPSC
    12352200