GSK-690693

MedChem Express

GSK-690693 [937174-76-0]

10

937174-76-0

Research Use Only

99.03

C21H27N7O3

425.48418

GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC 50 s of 2 nM, 13 nM, 9 nM for Akt1 , Akt2 and Akt3 , respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation [1] [2] [3] .

CC(O)(C)C#CC1=NC=C(OC[C@@H]2CNCCC2)C3=C1N=C(C4=NON=C4N)N3CC

-20°C,2°C to 8°C

12352200