Uzansertib (phosphate)

MedChem Express

Uzansertib (phosphate) [2088852-47-3]

10

2088852-47-3

Research Use Only

99.39

C26H29F3N5O7P

611.51

Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan- PIM kinase inhibitor with IC 50 s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines [1] .

O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O

2°C to 8°C

12352200