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Uzansertib phosphate

Research Use Only
T12477
TargetMol Chemicals
CAS Number2088852-47-3
Product group Chemicals
Molecular Weight611.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Uzansertib phosphate
  • Delivery Days Customer
    9
  • CAS Number
    2088852-47-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Uzansertib phosphate
  • Molecular Formula
    C26H29F3N5O7P
  • Molecular Weight
    611.51
  • Scientific Description
    Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).
  • Shelf life instruction
    3 years
  • SMILES
    O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.O=P(O)(O)O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Koblish H, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. PLoS One. 2018 Jun 21;13(6):e0199108.
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