NU7441 (KU-57788) [503468-95-9]

Selleck Chemicals

NU7441 (KU-57788) [503468-95-9]

9

Research Use Only

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 muM and 5 muM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.

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