KU-57788

MedChem Express

KU-57788 [503468-95-9]

10

503468-95-9

Research Use Only

99.95

C25H19NO3S

413.49

KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC 50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC 50 s of 5.0 and 1.7 microM, respectively [1] .

O=C1C=C(N2CCOCC2)OC3=C1C=CC=C3C4=CC=CC5=C4SC6=C5C=CC=C6

-20°C,2°C to 8°C

12352200