WYE-687

Selleck Chemicals

WYE-687 [1062161-90-3]

9

1062161-90-3

Research Use Only

...

WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kalpha (>100-fold) and PI3Kgamma (>500-fold).

-80°C

51202000