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WYE-687 [1062161-90-3]

WYE-687 [1062161-90-3]

T6732
TargetMol Chemicals
CAS Number1062161-90-3
DownloadMSDS
Product group Chemicals
Estimated Purity98.98%
Molecular Weight528.61
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    WYE-687 [1062161-90-3]
  • Delivery Days Customer
    9
  • CAS Number
    1062161-90-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    WYE-687
  • Estimated Purity
    98.98%
  • Molecular Formula
    C28H32N8O3
  • Molecular Weight
    528.61
  • Scientific Description
    WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 of 7 nM; it blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) without affecting P-AKT(T308). Its selectivity for mTOR is greater than PI3Kalpha (>100-fold) and PI3Kgamma (>500-fold).
  • Shelf life instruction
    3 years
  • SMILES
    COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(Cc4cccnc4)CC3)c2n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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