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IHC-P analysis of human spleen tissue using GTX21658 Chemokine Receptor D6 antibody.
IHC-P analysis of human spleen tissue using GTX21658 Chemokine Receptor D6 antibody.
IHC-P analysis of human spleen tissue using GTX21658 Chemokine Receptor D6 antibody.

Chemokine Receptor D6 antibody

GTX21658
GeneTex
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman, Mouse
TargetACKR2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Chemokine Receptor D6 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Peptide sequence is < 50 % identical to other chemokine receptors in this region.
  • Application Supplier Note
    WB: 1:500. IHC-P: 1:125. FACS: 2-6microl/106cells/50-100microl. ELISA: 1:50,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1238
  • Target name
    ACKR2
  • Target description
    atypical chemokine receptor 2
  • Target synonyms
    atypical chemokine receptor 2; C-C chemokine receptor D6; CCBP2; CC-chemokine-binding receptor JAB61; CCR10; CCR9; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine receptor CCR-10; chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; chemokine-binding protein D6; CMKBR9; D6; hD6
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDO00590
  • Protein Name
    Atypical chemokine receptor 2
  • Scientific Description
    This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
    Read more