CHIR-124

MedChem Express

CHIR-124 [405168-58-3]

10

405168-58-3

Research Use Only

99.05

C23H22ClN5O

419.91

CHIR-124 is a potent and selective Chk1 inhibitor with IC 50 of 0.3 nM, and also potently targets PDGFR and FLT3 with IC 50 s of 6.6 nM and 5.8 nM.

ClC1=CC2=C(NC(C(C3=NC4=C(C=CC=C4)N3)=C2N[C@@H]5CN6CCC5CC6)=O)C=C1

-20°C,2°C to 8°C

12352200