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Chk1, Mouse (sf9, His-GST)

Name: Chk1, Mouse (sf9, His-GST)
SKU: HY-P74253_M09
Availability: BackOrder

HY-P74253

Protein IDO35280

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
Chk1, Mouse (sf9, His-GST)
Delivery Days Customer
10
Certification
Research Use Only
Gene ID12649
Target name
Chek1
Target description
checkpoint kinase 1
Target synonyms
Chk1, rad27, serine/threonine-protein kinase Chk1, CHK1 checkpoint homolog, checkpoint kinase 1 homolog, rad27 homolog
Protein IDO35280
Protein Name
Serine/threonine-protein kinase Chk1
Scientific Description
Chk1 is a serine/threonine protein kinase that critically coordinates checkpoint-mediated cell cycle arrest and DNA repair in response to DNA damage or unreplicated DNA. It negatively regulates unperturbed cell cycle progression and protects genome integrity by phosphorylating key targets such as CDC25A, CDC25B, CDC25C, RAD51, TP53, histone H3.1, RB1, SPRTN, TLK1 and FANCE. Chk1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Chk1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
UNSPSC
41116100
Species
Mouse