Chloramphenicol

MedChem Express

Chloramphenicol [56-75-7]

10

56-75-7

Research Use Only

99.93

C11H12Cl2N2O5

323.132

Chloramphenicol is an orally active, potent and broad-spectrum antibiotic . Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha ( HIF-1alpha ) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor ( VEGF ) and glucose transporter 1 , eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research [1] [2] [3] .

O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)C(Cl)Cl

-20°C,2°C to 8°C

12352200