Chlorasquin [18921-73-8]
HY-121256
CAS Number18921-73-8
Product group Chemicals
Molecular Weight458.86
Overview
- SupplierMedChem Express
- Product NameChlorasquin [18921-73-8]
- Delivery Days Customer9
- CAS Number18921-73-8
- CertificationResearch Use Only
- Molecular FormulaC20H19ClN6O5
- Molecular Weight458.86
- Scientific DescriptionChlorasquin inhibits thymidylate synthetase with an approximate Ki value of 4.9 microM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents[1][2].
- SMILESO=C(C[C@H](NC(C1=CC=C(C=C1)NCC2=C(C3=C(N=C(N=C3C=C2)N)N)Cl)=O)C(O)=O)O
- UNSPSC12352200