CHM-1 [154554-41-3]

MedChem Express

CHM-1 [154554-41-3]

5

154554-41-3

Research Use Only

99.57

C16H10FNO3

283.25

CHM-1, a microtubule-destabilizing agent, inhibits tubulin polymerization. CHM-1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM-1 induces growth inhibition and apoptosis via G2-M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity[1][2][3].

O=C1C=C(C2=CC=CC=C2F)NC3=C1C=C4C(OCO4)=C3

-20°C,2°C to 8°C

12352200