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WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody. Loading : 20microg
WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody. Loading : 20microg
WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody. Loading : 20microg

ChREBP antibody

GTX30677
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMLXIPL
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Overview

  • Supplier
    GeneTex
  • Product Name
    ChREBP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:100. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID51085
  • Target name
    MLXIPL
  • Target description
    MLX interacting protein like
  • Target synonyms
    bHLHd14; carbohydrate response element binding protein; carbohydrate-responsive element-binding protein; CHREBP; class D basic helix-loop-helix protein 14; MIO; MLX; Mlx interactor; MONDOB; WBSCR14; Williams Beuren syndrome chromosome region 14; williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NP71
  • Protein Name
    Carbohydrate-responsive element-binding protein
  • Scientific Description
    This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Wang H et al., 2020 Jan, J Cell Mol Med
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  • Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome. Dreja T et al., 2010 Feb, Diabetologia
    Read more