
WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody. Loading : 20microg
ChREBP antibody
GTX30677
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMLXIPL
Overview
- SupplierGeneTex
- Product NameChREBP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:100. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51085
- Target nameMLXIPL
- Target descriptionMLX interacting protein like
- Target synonymsbHLHd14; carbohydrate response element binding protein; carbohydrate-responsive element-binding protein; CHREBP; class D basic helix-loop-helix protein 14; MIO; MLX; Mlx interactor; MONDOB; WBSCR14; Williams Beuren syndrome chromosome region 14; williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
- HostRabbit
- IsotypeIgG
- Protein IDQ9NP71
- Protein NameCarbohydrate-responsive element-binding protein
- Scientific DescriptionThis gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Wang H et al., 2020 Jan, J Cell Mol MedRead more
- Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome. Dreja T et al., 2010 Feb, DiabetologiaRead more