CHRFAM7A Polyclonal Antibody

Reddot Biotech

CHRFAM7A Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

CHRFAM7A

CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion

CHRNA7, CHRNA7-DR1, D-10, NACHRA7, CHRNA7-FAM7A fusion protein, CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion, CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion, Neuronal acetylcholine receptor subunit alpha-7, alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid, alpha-7 nicotinic cholinergic receptor subunit

Rabbit

IgG

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Human, Mouse, Rat

-20°C

12352203