Western Blot analysis of A172 and A549 cell using CHRNA2 Polyclonal Antibody at dilution of 1:950
Western Blot analysis of A172 and A549 cell using CHRNA2 Polyclonal Antibody at dilution of 1:950
CHRNA2 Polyclonal Antibody
E-AB-16340
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCHRNA2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionNicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
- UNSPSC12352203