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Chromogranin C antibody

Name: Chromogranin C antibody
SKU: GTX116446_G10
Availability: BackOrder

GTX116446

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetSCG2

Overview

Supplier
GeneTex
Product Name
Chromogranin C antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.26 mg/ml
Conjugate
Unconjugated
Gene ID7857
Target name
SCG2
Target description
secretogranin II
Target synonyms
CHGC, EM66, SN, SgII, secretogranin-2, chromogranin-C, secretoneurin
Host
Rabbit
Isotype
IgG
Protein IDP13521
Protein Name
Secretogranin-2
Scientific Description
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation. Lin Z et al., 2022 Sep, Adv Sci (Weinh)
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Characterization of blood-derived exosomal proteins after exercise. Xiang H et al., 2020 Sep, J Int Med Res
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CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. Moro A et al., 2020 Aug, PLoS Biol
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Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma. Federico A et al., 2020 Sep 25, Mol Ther Oncolytics
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Kaposis Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells. Valiya Veettil M et al., 2020 Mar 31, J Virol
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Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. Peitsch WK et al., 2014, PLoS One
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