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ProductsBack/Chromogranin C antibody

Chromogranin C antibody

GTX116446
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetSCG2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Chromogranin C antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.26 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7857
  • Target name
    SCG2
  • Target description
    secretogranin II
  • Target synonyms
    CHGC; chromogranin-C; EM66; secretogranin-2; secretoneurin; SgII; SN
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP13521
  • Protein Name
    Secretogranin-2
  • Scientific Description
    The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation. Lin Z et al., 2022 Sep, Adv Sci (Weinh)
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  • Characterization of blood-derived exosomal proteins after exercise. Xiang H et al., 2020 Sep, J Int Med Res
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  • CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. Moro A et al., 2020 Aug, PLoS Biol
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  • Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma. Federico A et al., 2020 Sep 25, Mol Ther Oncolytics
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  • Kaposis Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells. Valiya Veettil M et al., 2020 Mar 31, J Virol
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  • Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. Peitsch WK et al., 2014, PLoS One
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