Chromogranin C antibody detects SCG2 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. Chromogranin C antibody (GTX116446) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
Chromogranin C antibody detects SCG2 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. Chromogranin C antibody (GTX116446) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
Chromogranin C antibody
GTX116446
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSCG2
Overview
- SupplierGeneTex
- Product NameChromogranin C antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.26 mg/ml
- ConjugateUnconjugated
- Gene ID7857
- Target nameSCG2
- Target descriptionsecretogranin II
- Target synonymsCHGC, EM66, SN, SgII, secretogranin-2, chromogranin-C, secretoneurin
- HostRabbit
- IsotypeIgG
- Protein IDP13521
- Protein NameSecretogranin-2
- Scientific DescriptionThe protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lin Z, Li Y, Hang Y, et al. Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation. Adv Sci (Weinh). 2022,9(27):e2202263. doi: 10.1002/advs.202202263Read this paper
- Xiang H, Chen S, Zhou J, et al. Characterization of blood-derived exosomal proteins after exercise. J Int Med Res. 2020,48(9):300060520957541. doi: 10.1177/0300060520957541Read this paper
- Moro A, van Woerden GM, Toonen RF, et al. CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. PLoS Biol. 2020,18(8):e3000826. doi: 10.1371/journal.pbio.3000826Read this paper
- Federico A, Steinfass T, Larribère L, et al. Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma. Mol Ther Oncolytics. 2020,18:83-99. doi: 10.1016/j.omto.2020.06.001Read this paper
- Valiya Veettil M, Krishna G, Roy A, et al. Kaposi's Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells. J Virol. 2020,94(8). doi: 10.1128/JVI.01692-19Read this paper
- Peitsch WK, Doerflinger Y, Fischer-Colbrie R, et al. Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. PLoS One. 2014,9(2):e89491. doi: 10.1371/journal.pone.0089491Read this paper
Datasheet
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